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Generic Glucophage comes in tablets to take by mouth. It usually is taken two or three times a day with meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Generic Glucophage exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Metformin hydrochloride extended-release tablets should be swallowed whole. Do not break, chew, or crush. Continue to take Metformin hydrochloride even if you feel well. Do not stop taking Metformin hydrochloride without talking to your doctor.

Although side effects from Metformin hydrochloride are not common, they can occur. If you have any of these symptoms, eat or drink a food or beverage with sugar in it, such as hard candy or fruit juice, and call your doctor immediately; symptoms of low blood sugar (hypoglycemia) include: * shakiness * dizziness * rapid heartbeat * sweating or confusion * blurred vision * headache * numbness or tingling of the mouth * weakness * fatigue * pale color - sudden hunger If you have any of these symptoms, call your doctor immediately; symptoms of high blood sugar (hyperglycemia) include: * thirst * dry mouth * tiredness * flushing * dry skin * frequent urination * loss of appetite * trouble breathing

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Do not take any other medicine unless prescribed or approved by your doctor . When you are taking metformin, it is especially important that your health care professional know if you are taking any of the following: * Alcohol Small amounts of alcohol taken with meals do not usually cause a problem; however, either larger amounts of alcohol taken for a long time or a large amount of alcohol taken in one sitting without food can increase the effect of metformin. This can keep the blood sugar low for a longer period of time than normal * Amiloride (e.g., Midamor) or * Calcium channel blocking agents (amlodipine [e.g., Norvasc], bepridil [e.g., Bepadin], diltiazem [e.g., Cardizem], felodipine [e.g., Plendil], flunarizine [e.g., Sibelium], isradipine [e.g., DynaCirc], nicardipine [e.g., Cardene], nifedipine [e.g., Procardia], nimodipine [e.g., Nimotop], verapamil [e.g., Calan]) or * Cimetidine (e.g., Tagamet) or * Digoxin (heart medicine) or * Furosemide (e.g., Lasix) or * Morphine (e.g., M S Contin) or * Procainamide (e.g., Pronestyl) or * Quinidine (e.g., Quinidex) or * Quinine (malaria medicine) or * Ranitidine (e.g., Zantac) or * Triamterene (e.g., Dyrenium) or * Trimethoprim (e.g., Proloprim) or * Vancomycin (e.g., Vancocin)Use with metformin may cause high blood levels of metformin, which may increase the chance of low blood sugar or side effects.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children.